endometrin is a progesterone suppository used three times a day instead of a PIO injection. It’s far less messy than the greasy compounded suppositories and, according to my RE, is well absorbed and very effective.
I have a box and a half of it left from FET #2 that I can’t use because I’ve been switched back to PIO for this cycle.
Any reason why he switched you back? We’re gearing up for an FET and i was told they don’t do PIO as a matter of course for FETs (this is our first)….we did PIO with our fresh cycle, along with suppositories.
According to Dr. N, when they did their review of the previous year’s cases they found no difference in rate of pregnancies between PIO and endometrin, but they did find a slight increase in sustained pregnancies (her term) with PIO. The doctors in the practice decided to head off patient questions and debate over differing methods and use PIO across the board.
I know the day I started miscarrying, they sent me to the local compounding pharmacy to get PIO right away before they even had any test results.
I didn’t really ask for details since I’d planned on requesting PIO for this cycle anyway, so I don’t know the details on the difference between the two and I have no idea how a FET cycle might differ from an IVF cycle in terms of progesterone support needs and I have no idea how big of a data pool they based their decision on. I think eliminating a point of concern over one method vs another was a not insignificant part of their decision just to keep down the second guessing and hindsight worries. As I’ve said in the past, I was a literature major which should tell you everything you need to know about my medical knowledge. If you have questions, I’d make sure your RE answers them to your satisfaction before getting into your FET. Fertility treatment is as much an art as it is a science, after all. For me, I KNOW I got pregnant once while using PIO and I need every bit of peace of mind I can get going forward. It’s a “it ain’t broke so don’t fix it” situation for me.
Am just catching up after taking december, jan, feb & most of march off from blog reading. I’m sorry about the miscarriage- I had hoped it would work after all you were doing to psyche yourself up to get back into the IVF game again- life can be so cruel sometimes. But I’m glad to see your same humor and grace still there, if more battle-scarred. Thinking of you and S. Hope todays appointment goes well and if it does, when is the next FET scheduled for?